Individual and combined associations between cardiorespiratory fitness and grip strength with frequent mental disorders
A prospective cohort study in the UK Biobank.
Depression and anxiety are common mental disorders that increase physical health risks and are a major cause of disability worldwide. Different forms of physical fitness could be modifiable risk factors for common mental disorders in the population. We investigated associations between individual and combined markers of cardiorespiratory fitness and grip strength with the occurrence of common mental disorders.
A seven year prospective cohort study of 152,978 UK biobank participants. An exercise test and a dynamometer were used to measure cardiorespiratory fitness and gripping strength, respectively. We used the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales to estimate the incidence of more common mental disorders at follow-up.
Low and moderate cardiorespiratory fitness and grip strength were associated with a higher likelihood of depression or anxiety compared to high cardiorespiratory fitness and grip strength. People in the lowest group for both cardiorespiratory fitness and grip strength were most likely to have depression and anxiety.
Objective cardiorespiratory and muscular fitness markers represent modifiable risk factors for common mental disorders. Public health strategies to reduce common mental disorders could include combinations of aerobic and resistance activities.
Published in BMC Medicine volume, November 18, 2020